Prehabilitation


Authors: Š. Lednický;  D. Cibula;  Š. Slabá
Authors‘ workplace: Gynekologicko‑porodnická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. A. Martan, DrSc.
Published in: Ceska Gynekol 2020; 85(5): 352-356
Category: Review article

Overview

Objective: The main purpose of this article was to provide available information’s about concept of prehabilitation aiming on its effectiveness and benefits it provides to oncological patients.

Design: Review.

Setting: Department of Gynaecology and Obstetrics, First Faculty of Medicine, Charles University and General University Hospital in Prague.

Methods: We performed a research of available literature from 1998 to the present using PubMed database, focusing on keywords. We aimed on analysis of the results from prospective studies.

Results: Prehabilitation refers to interventions aiming on increasing resilience and functional capacity before well-known stress event (surgical performance). The mainstay of prehabilitation is physiotherapy combined with nutritional or psychological support. A positive effect of combined preoperative intervention was demonstrated. Prehabilitation increases the patient‘s functional capacity, reduces the number of perioperative and postoperative complications and shortens hospital length of stay. It also improves adherence of cancer patients to treatment, reduces anxiety or depression and reduces overall stress levels.

Conclusion: Prehabilitation may significantly improve quality of life. Moreover, it reduces costs of oncological treatment.

Keywords:

Quality of life – prehabilitation – oncology – functional capacity


Sources

1.    American Cancer Society. Cancer Facts & Figures 2010. Atlanta, GA, USA: American Cancer Society, 2010.

2.    Andreyev, HJ., Norman, AR., Oates, J., Cunningham, D. Why do patients with weight loss have a worse outcome when undergoing chemotherapy for gastrointestinal malignancies., Eur J Cancer, 1998. doi: 10.1016/s0959-8049(97)10090-9.

3.    Arends, J., Bachmann, P., Baracos, V., et al. ESPEN guidelines on nutrition in cancer patients. Clin Nutr, 2017. doi: 10.1016/j.clnu.2016.07.015.

4.    Banugo, P., Amoako, D. BJA Education, 2017, 17(12), doi.:10.1093/bjaed/mkx032.

5.    Barberan-Garcia, A., Navarro-Ripoll, R., Sánchez-Lorente, D., et al. Cost-effectiveness of technology-supported multimodal prehabilitation program in moderate-to-high patients undergoing lung cancer resection:ranodmised controlled trial protocol. BMC Health Serv Res, 2020, doi:10.1186/s12913-020-05078-9.

6.    Barberan-Garcia, A., Ubre, M., Roca, J., et al. Personalised prehabilitation in high-risk patients undergoing elective major abdominal surgery: a randomized blinded controlled trial. Ann Surg, 2018. doi: 10.1097/SLA.0000000000002293.

7.    Beck, A., Vind Thaysen, H., Hasselholt Soegaard, C., et al. Prehabilitation in cancer care: patient‘s ability to prepare for major abdominal surgery. Scand J Caring Sci, 2020, doi:10.1111/scs.12828.

8.    Benzo, R., Wigle, D., Novotny, P., et al. Preoperative pulmonary rehabilitation before lung cancer resection: results from two randomized studies. Lung Cancer, 2011, 74, p. 441–445.

9.    Biglia, N., Zanfagnin, V., Daniele, A., et al. Lower body lymphedema in patients with gynecologic cancer. Anticancer Res, 2017. doi: 10.21873/anticanres.11785.

10. Blackwell, JEM., Doleman, B., Boereboom, CL.,et al. High-intensity interval training produces a significant improvement in fitness in less than 31 days before surgery for urological cancer: a randomised control trial. Prostate cancer and prostatic diseases, 2020.

11.  Bobbio, A., Chetta, A., Ampollini, L., et al. Preoperative pulmonary rehabilitation in patients undergoing lung resection for non-small cell lung cancer. Eur J Cardio-thorac Surg, 2008, 33, p. 95–98.

12. Burke, SM., Brunet, J., Sabiston, CM., et al. Patients’ perceptions of quality of life during active treatment for locally advanced rectal cancer: the importance of preoperative exercise. Support Care Cancer, 2013, 21, p. 3345–3353.

13. Carli, F., Brown, R., Kennepohl, S. Prehabilitation to enhance postoperative recovery for an octogenarian following robotic-assisted hysterectomy with endometrial cancer. Can J Anaest, 2012, 59, p. 779–784.

14. Carli, F., Charlebois, P., Stein, B., et al. Randomized clinical trial of prehabilitation in colorectal surgery. Br J Surg, 2010, 97, p. 1187–1197.

15. Cianci, S., Tarascio, M., Rosati, A.,et al. Sexual function and quality of life of patients affected by ovarian cancer. Minerva Med, 2019. doi: 10.23736/S0026-4806.19.06080-4.

16. https://clinicaltrials.gov/ct2/results?cond=Ovarian+Cancer&term=prehabilitation&cntry=&state=&city=&dist=

17. Comb, J. Role of stomacare nurse: Patients with cancer and colostomy. Brit J Nursing, 2020, 12(14).

18. Cortés-Guiral, D., Mohamed, F., Glehen, O., Passot, G. Prehabilitation of patients undergoing cytoreductive surgery (CRS) and hypertemic intraperitoneal chemotherapy (HIPEC) for peritoneal malignancy. Eur J Surg Oncol, 2020. doi: 10.1016/j.ejso.2020.01.032.

19. Daroszewski, C., Stasiewicz, M., Jazwinska-Tarnawska, E., et al. Quality of life in patients with advanced non-small-cell lung cancer receiving palliative chemotherapy. Adv Exp Med Biol, 2019. doi: 10.1007/5584_2019_346.

20. Divisi, D., Di Francesco, C., Di Leonardo, G., Crisci, R. Preoperative pulmonary rehabilitation in patients with lung cancer and chronic obstructive pulmonary disease. Eur J Cardiothorac Surg, 2013, 43, p. 293–296.

21. Frobes, CC., Swan, F., Greenley, SL., et al. Physical activity and nutrition interventions for older adults with cancer: a systematic review. J Cancer Surv, 2020. doi: 10.1007/s11764-020-00883-x.

22. Ghirardi, V., Moruzzi, MC., Bizzarri, N., et al. Minimal residual disease at primary debulking surgery versus complete tumor resection at interval debulking surgery in advanced epithelial ovarian cancer: A survival analysis. Gynecol Oncol, 2020. doi: 10.1016/j.ygyno.2020.01.010.

23. Gillis, C., Buhler, K., Bresee, L., et al. Effects of nutritional prehabilitation, with and without exercise, on outcomes of patients who undergo colorectal surgery: a systematic review and meta-analysis. Gastroenterology, 2018, p. 391–410.e4. doi:10.1053/j.gastro.2018.05.012.

24. Gillis, C., Li, C., Lee, L., et al. Prehabilitation versus rehabilitation: a randomised control trial in patients undergoing colorectal resection for cancer. Anesthesiology, 2014. doi: 10.1097/ALN. 0000000000000393.

25. Goode, PS. Efficacy of an assisted low-in-tensity programme of perioperative pelvic floor muscle training in improving the recovery of continence after radical prostatectomy: a randomized controlled trial. BJU Int, 2012, 110, p. 1010–1011.

26. Hamel, MB., Henderson, WG., Khuri, SF., et al. Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery. J Am Geriatr Soc, 2005. doi: 53:424–9. 10.1111/j.1532-5415.2005.53159.x.

27. Chiofalo, B., Bruni, S., Certelli, C., et al. Primary debulking surgery vs. Interval debulking surgery for advanced ovarian cancer: review of the literature and meta-analysis, Minerva Med, 2019. doi: 10.23736/S0026-4806.19.06078-6.

28. Inoue, J., Ono, R., Makiura, D., et al. Prevention of postoperative pulmonary complications through intensive preoperative respiratory rehabilitation in patients with esophageal cancer. Dis Esophagus, 2013, 26, p. 68–74.

29. Kim, do J., Mayo, NE., Carli, F., et al. Responsive measures to prehabilitation in patients undergoing bowel resection surgery. Tohoku J Exp Med, 2009, 217, p. 109–115.

30. Li, C., Carli, F., Lee, L., et al. Impact of trimodal prehabilitation program on functional recovery after colorectal cancer surgery: a pilot study. Surg Endosc, 2013, doi:10.1007/s00464-012-2560- 5.

31. Li, MH., Bolshinsky, V., Ismail, H., et al. A cross-sectional survey of Australian anesthetists’ and surgeons’ perceptions of preoperative risk stratification and prehabilitation. Can J Anaesth, 2019, 66, p. 388–405.

32. Lin, HS., Watts, JN., Peel, NM., Hubbard, RE. Frailty and post-operative outcomes in older surgical patients: a systematic review. BMC Geriatrics, 2016, 16(1), doi:10.1186/s12877-016-0329-8

33. Ljungqvist, O., Scott, M., Fearon, KC. Enhanced recovery after surgery. JAMA Surg, 2017, 152(3), 292, doi:10.1001/jamasurg.2016.4952.

34. Mahoney, FI., Barthel, D. Functional evaluation: the Barthel Index. Maryland State Med J, 1965, 14, p. 56–61. Použito se svolením.

35. Marshal, KM., Loeliger, J., Nolte, L., et al. Prevalence of malnutrition and impact on clinical outcomes in cancer services: A comparison of two time points. Clin Nutrition, 2018. doi: 10.1016/j.clnu.2018.04.007.

36. Mavros, MN., Athanasiou, S., Gkegkes, ID., et al. Do psychological variables affect early surgical recovery? PLoS One, 2011.

37. Mayo, NE., Feldman, L., Scott, S., et al. Impact of preoperative change in physical function on postoperative recovery: argument supporting prehabilitation for colorectal surgery. Surgery. doi: 2011;150:505-514.

38. McKenna, NP., Bews, KA., B al-Refaie, W., et al. Assessing malnutrition before major oncologic surgery: Onesize does not fit all. J Am Coll Surg, 2020, doi:10.1016/j.jamcollsurg.2019.12.034.

39. Minnella, EM., Awasthi, R., Loiselle, SE., et al. Effect of exercise and nutrition prehabilitation on functional capacity in esophagogastric cancer surgery: A randomised clinical trial. JAMA Surg, 2018, doi:10.1001/jamasurg.2018.1645.

40. Minnella, EM., Bousquet-Dion, G., Awasthi, R., et al. Multimodal prehabilitation improves functional capacity before and after colorectal surgery for cancer: a five-year research experience. Acta Oncol, 2017, 56, p. 295–300.

41. Morano, MT., Araujo, AS., Nascimento, FB., et al. Preoperative pulmonary rehabilitation versus chest physical therapy in patients undergoing lung cancer resection: a pilot randomized controlled trial. Arch Phys Med Rehabil, 2013, 94, p. 53–58.

42. Nepogodiev, D., Martin, J., Biccard, B., et al. Global burden of postoperative death. Lancet, 2019, 393(10170), p. 401. doi:10.1016/s0140-6736(18)33139-8.

43. Ohkura, Y., Ichikura, K., Shindoh, J., et al. Relationship between psychological distress and health-related quality of life at each point of the treatment of esophageal cancer. Esophagus, 2020. doi: 10.1007/s10388-019-00710-y.

44. Scalo, JF., Rascati, KL. Trends and issues in oncology costs. Expert Rev Pharmacoeconom Outcomes Res, 2013, 14(1), p. 35–44. doi:10.1586/14737167.2014.864561.

45. Sekine, Y., Chiyo, M., Iwata, T., et al. Perioperative rehabilitation and physiotherapy for lung cancer patients with chronic obstructive pulmonary disease. Jpn J Thorac Cardiovasc Surg, 2005, 53, p. 237–243.

46. Schier, R., Levett, D., Riedel, B. Prehabilitation: The next challenge for anesthesia teams. Eur J Anaesthesiol, 2020. doi: 10.1097/EJA.0000000000001167.

47. Silver, JK. Prehabilitation may help mitigate an increase in COVID-19 peri-pandemic surgical morbidity and mortality. Am J Phys Med Rehabil, 2020. doi: 10.1097/PHM.0000000000001452.

48. Silver, JK. Cancer prehabilitation and its role in improving health outomes and reducing health care costs. Semin Oncol Nurs, 2015. doi: 10.1016/j.soncn.2014.11.003.

49. Silver, JK. Prehabilitation could save lives in a pandemic. BMJ, 2020, 1386. doi: 10.1136/bmj.m1386.

50. Turrentine, FE., Wang, H., Simpson, VB., et al. Surgical risk factors, morbidity, and mortality in elderly patients. J Am Coll Surg, 2006, 203, p. 865–877. doi: 10.1016/j.jamcollsurg.2006.08.026.

51. Vonk Noordegraaf, A., Anema, J., van Mechelen, W., et al. A personalised health programme reduces the duration until return to work after gynaecological surgery: results of a multicentre randomised trial. BJOG, 2014, 121, p. 1127–1136.

52. Watanabe, T., Momosaki, R., Suzuki, S., Abo, M. Preoperative rehabilitation for patients undergoing colorectal cancer surgery: a retrospective cohort study. Supportive Care in Cancer, 2020, 28, p. 2293–2297.

53. West, MA., Loughney, L., Lythgoe, D., et al. Effect of prehabilitation on objectively measured physical fitness after neoadjuvant treatment in preoperative rectal cancer patients: a blinded interventional pilot study. Brit J Anaesth, 2005, 114(2), p. 244–251. doi:10.1093/bja/aeu318.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account