Osteogenesis imperfecta/ Ehlers-Danlosův syndrom (COL1-asociované onemocnění) v těhotenství


Authors: A. Šinská ;  E. Hostinská ;  R. Pilka
Authors‘ workplace: Department of Obstetrics and Gynecology, Faculty of Medicine, Palacky University and University Hospital Olomouc
Published in: Ceska Gynekol 2022; 87(6): 396-400
Category: Case Report
doi: 10.48095/cccg2022396

Overview

Ehlers-Danlosův syndrom je označení pro skupinu onemocnění pojivových tkání, které může během gravidity vést k řadě komplikací. Manifestuje se hyperextensibilní kůži, špatným hojením, hyperflexibilitou nebo vyšším rizikem poškození různých orgánů (ruptura dělohy, disekce aorty). Kombinace Ehlers-Danlosova syndromu a osteogenesis imperfecta je velmi zřídkavá (dle Orphanetu < 1/1 000 000). Prezentujeme kazuistiku gravidity, u pacientky s osteogenesis imperfecta/Ehlers-Danlosovým syndromem, komplikovanou dilatací aorty. Naší kazuistikou chceme poukázat na možné komplikace související s graviditou u tohoto velmi raritního, ale extrémně závažného syndromu.

Klíčová slova:

těhotenství – osteogenesis imperfecta – disekce aorty – Ehlers-Danlosův syndrom – COL1-asociované onemocnění


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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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