L-arginin in prevention and treatment of pre-eclampsia

Authors: L. Vacula
Authors‘ workplace: Gynekologicko-porodnické oddělení, Kroměřížská nemocnice, a. s., Kroměříž, primář MUDr. J. Přibík
Published in: Ceska Gynekol 2013; 78(2): 181-186


It is to show the possible relationship between the patofysiology of pre-eclampsia in the body of a human with a relative lack of L-arginine and its potential connection with a nitrogen metabolism. This study also suggests the further utilization of above mentioned knowledges in a prevention and a treatment of pre-eclampsia.

Literary overview.

Gynaecology and Obstetric Department of the Hospital Kromeriz, Inc., Kromeriz.

The background research of studies and issues published already in medical professional journals, bulletins and medical web databases.

To provide L-arginine to pregnant women as a dietary supplement concerns no risk and is an easy precaution. L-arginine can reduce the occurrance of pre-eclampsia in women with a potential high risk of its developement. The most important transmitter substance that makes L-arginine work is the dioxide nitrogen. So far, it has been the outmost possibility how to influence the patofysiology of Pre-eclampsia The lack of L-arginine and its influence on the nitrogen metabolism is likely, but there is also a great need for further research.

pre-eclampsia – L-arginine – dioxide nitrogen – NO synthase – dysfunction of endothelium – urea cycle


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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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