Role of fatty acids in sperm membrane


Authors: X. Štramová 1;  R. Hampl 2;  J. Štěpán 2;  R. Kanďár 1
Authors‘ workplace: Fakulta chemicko-technologická, Katedra biologických a biochemických věd, Univerzita Pardubice
Published in: Ceska Gynekol 2014; 79(2): 103-106

Overview

One of causes of male infertility is reduced sperm motility. Reactive oxygen species (ROS) play significant role for physiological sperm function. Oxidative stress occurs when the production of potentially destructive ROS exceeds the natural antioxidant defences, resulting in cell damage. Sperm phospholipid polyunsaturated fatty acids are particularly susceptible to peroxidative damage by free radicals. Detrimental effects of lipid peroxidation should decrease sperm quality and be responsible of fertility problems.

The review deals with sperm membrane composition, importance of fatty acids and prevention possibilities of oxidative cell damage.

Keywords:
sperm membrane, fatty acids, lipoperoxidation, infertility, antioxidants


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Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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