Various approaches of endometrial preparation for frozen-thawed embryo transfer
Authors:
J. Vodička 1; M. Dvořan 1; K. Smékalová 1; L. Michnová 2; P. Hejtmánek 1; K. Lehnertová 1; J. Dostál 1
; M. Pešková 1; M. Annenková 1; R. Pilka 1
Authors‘ workplace:
Porodnicko-gynekologická klinika LF UP a FN, Olomouc, přednosta prof. MUDr. R. Pilka, Ph. D.
1; IVF Clinic, Olomouc, vedoucí lékař MUDr. Š. Machač, Ph. D.
2
Published in:
Ceska Gynekol 2018; 83(1): 24-28
Overview
Objective:
Various approaches of endometrial preparation for frozen-thawed embryo transfer.
Design:
Retrospective analysis.
Setting:
Department of Obstetric and Gyneacology, Faculty of Medicine, Palacky University, University Hospital Olomouc.
Methods:
Effectivity of frozen-thawed embryo transfers was carried out between January and August 2017 in the IVF unit at the University Hospital Olomouc. Results were compared among groups A, B, C with various approaches of endometrial preparation. Group A – natural ovulating cycle, group B – artificial cycle with oral estrogen, vaginal gestagen and group C – artificial cycle with transdermal estrogen and vaginal gestagen. One blastocyst (two blastocyst in five cycles) was transferred on day 6 post ovulation (group A) or after 6 days of using gestagens (group B, C).
Results:
The highest pregnancy rate was observed in group C (56%), similar pregnancy rate was found in group B (52%) and the lowest was seen in group A (22%). All pregnancies in group A continued over 12 weeks, in group B continued 57 percent and in group C continued 56 percent of pregnancies.
Conclusion:
Frozen-thawed embryotransfers in natural cycles are highly time-consuming. Our study has demonstrated the lowest effectivity of frozen-embryotransfer in natural cycles. Artificial cycles managed by oral or transdermal form of estrogen have shown better results.
Keywords:
frozen-thawed embryotransfer, natural cycle, artificial cycle, pregnancy rate
Sources
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Labels
Paediatric gynaecology Gynaecology and obstetrics Neonatology Paediatrics Reproduction medicineArticle was published in
Czech Gynaecology
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