Prevention of early-onset neonatal group B streptococcal infection: neonatal outcome after introduction of national screening guideline

Authors: O. Šimetka 1;  M. Pětroš 1;  H. Podešvová 2
Authors‘ workplace: Porodnicko-gynekologická klinika, FN Ostrava, přednosta MUDr. O. Šimetka 1;  Oddělení neonatologie, FN Ostrava, primářka MUDr. R. Kolářová 2
Published in: Ceska Gynekol 2010; 75(1): 41-46


To evaluate the effectiveness of introduction of national guideline to prevent early-onset group B streptococcal (EOGBS) disease, number of screened women and incidence of GBS colonization.

Retrospective cohort study.

Department of Obstetrics and Gynaecology, Department of Neonatology, University Hospital Ostrava.

Subject and method:
We reviewed 8484 consecutive term pregnancies of women who delivered in our hospital, between years 1999-2001 before the introduction of guideline and years 2003-2005 following the guideline.

In group 1999-2001 there were 12/3581 (3.35 š) neonates with EOGBS infection in which 7/3581 (1.96 š) had invasive disease. In group 2003-2005 there were 14/4903 (2.86 š) neonates with EOGBS infection (p=68,33%), in which 6/4903 (1,22 š) had invasive disease (p=39,52%). Number of screened women in years 2003-2005 increased from 40% to 65%, and 69% respectively. There were 577/3019 (19%) of GBS colonized women.

There was 15% decrease of EOGBS disease following the introduction of guideline. Number of screened women increased by 29% in three-year period. GBS colonization in pregnant women is 19%.

Key words:
group B streptococcus, GBS prophylaxis, screening, guideline.


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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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