History and current trends in the treatment of idiopathic overactive bladder

Authors: Habeš D. 1;  Leško D. 1;  Štěpán M. 1;  Špaček J. 2;  Kestřánek J. 1
Authors‘ workplace: Porodnická a gynekologická klinika LF UK a FN Hradec Králové 1;  Urologická klinika LF UK a FN Hradec Králové 2
Published in: Ceska Gynekol 2021; 86(4): 284-290
Category: Review Article
doi: https://doi.org/10.48095/cccg2021284


Objective: Historical and current view on the therapy of overactive bladder. Methods: This review summarizes the historical approach and current therapy of overactive bladder. The articles were gathered from Pubmed and Scopus databases. Studies published before December 2020 were used for the review. Results and Conclusion: Overactive bladder is a condition that quite a lot reduces the quality of life of our patients. Our therapeutic approach starts with non-pharmacological treatment, such as pelvic floor exercises. The next step is a pharmacological approach. The entry level drug is trospium. If the effect is not sufficient, propiverine, solifenacin, fesoterodine, darifenacin or mirabegron are used. Electrostimulation or botulinum toxin A application is an option only in cases that didn’t respond to pharmacological treatment. It is safe to say, that in the end, there is a way of reducing the severity of overactive bladder symptoms for every  patient.


overactive bladder – urgency – anticholinergics – mirabegron – electrostimulation – botulinum toxin A


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