Prevention of de novo adhesion formation in patients with Asherman's syndrome


Authors: Boudová B.;  Lisá Z.;  Richtárová A.;  Kužel D.;  Mára M.
Authors‘ workplace: Gynekologicko-porodnická klinika 1. LF UK a VFN v Praze
Published in: Ceska Gynekol 2021; 86(4): 273-278
Category: Review article
doi: 10.48095/cccg2021273

Overview

Objective: To summarize recent data and knowledge of secondary prevention of the recurrence of intrauterine adhesions in patients with Asherman‘s syndrome. Methods: Analysis of literature evidence and clinical experience of the authors. Results: Asherman‘s syndrome is iatrogenic disease with problematic therapy. One of the basic issues is a need for repeated surgical interventions since the recurrence of adhesions is very frequent. Secondary prevention is a crucial factor for successful therapy in these patients. The methods applied include second--look hysteroscopy, hormonal treatment and different types of barriers. To compare their efficacy is difficult and the results of meta-analysis are contradictory. Conclusion: There are many different possibilities of secondary prevention of the recurrence of intrauterine adhesions; unfortunately, none of them is perfect. The usage of solid or semi-solid barriers in combination with the support of endometrium regeneration with hormonal therapy seems most reasonable.

Keywords:

Asherman‘s syndrome – hysteroscopy – intrauterine adhesions – prevention


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Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine

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