Assisted reproduction in patients with Klinefelter syndrome
Authors:
K. Crha 1
; M Ješeta 1
; R. Pilka 2
; M. Kašík 3
; L. Mekiňová 1
; J. Vodička 2
; T. Crha 1
Authors‘ workplace:
Gynekologicko-porodnická klinika LF MU a FN Brno
1; Porodnicko-gynekologická klinika LF UP a FN Olomouc
2; Urologická klinika LF MU a FN Brno
3
Published in:
Ceska Gynekol 2022; 87(2): 133-136
Category:
Review Article
doi:
https://doi.org/10.48095/cccg2022133
Overview
Objective: The goal of this article is to present the current knowledge of Klinefelter syndrome and its impact on male reproductive function as well as the current treatment options. Methods: PubMed/Medline, WoS and Scopus were searched for articles indexed until November 2021. Text: Klinefelter syndrome is a chromosomal aberration with an additional X chromosome in males. This may adversely affect testicular growth and spermatogenesis, thus resulting in male infertility. Recently, new knowledge has appeared about the treatment of male infertility. Conclusion: Interdisciplinary approach enables early diagnosis and treatment of patients with Klinefelter syndrome. Assisted reproductive technology is essential for infertility treatment in patients with Klinefelter syndrome.
Keywords:
genetic testing – assisted reproduction – Aneuploidy – disorders of spermatogenesis – male sterility – Klinefelter syndrome
Sources
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Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
2022 Issue 2
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