SARS-CoV-2 placentitis – report of two cases and review of the literature

Authors: M. Daumová 1,2 ;  Hadravská Š. 1,2;  Peteříková Straková A. 1;  Vaněček T. 1,2;  Matas M. 3;  Korečko V. 4
Authors‘ workplace: Šiklův ústav patologie, LF UK a FN Plzeň 1;  Bioptická laboratoř s. r. o., Plzeň 2;  Neonatologické oddělení, LF UK a FN Plzeň 3;  Gynekologicko-porodnická klinika LF UK a FN Plzeň 4
Published in: Ceska Gynekol 2022; 87(2): 111-117
Category: Case Report
doi: 10.48095/cccg2022111


Covid-19 disease caused by severe acute respiratory syndrome 2 coronavirus (SARS-CoV-2) continues to be a global public health problem. Since the pandemic outbreak in early 2020, a number of cases have been reported in pregnant women whose infection has led to severe complications including preterm birth, miscarriage, intrauterine growth restriction or intrauterine fetal demise. The results of the current studies suggest that the transplacental transmission of infection from mother to fetus is a rare event and that the complications listed above are more likely due to damage of placental tissue. In this article, we describe two cases of SARS-CoV-2 placentitis with special consideration to the morphology and differential dia­gnosis of this newly defined entity.


Placenta – SARS-CoV-2 – COVID-19 – placentitis – histiocytic intervillositis


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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine

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